Contact your doctor immediately if you experience a severe allergic reaction. Symptoms include difficulty breathing, swelling of your face, lips, tongue, or throat, and hives.
Severe Side Effects Requiring Immediate Attention
Seek immediate medical help if you develop: Severe skin reactions (such as Stevens-Johnson syndrome or toxic epidermal necrolysis), characterized by blistering, peeling skin, and fever; signs of kidney problems (such as decreased urination, swelling, or unusual fatigue); jaundice (yellowing of the skin or eyes); or unusual bleeding or bruising.
Persistent or Worsening Symptoms
While Bactrim often improves symptoms quickly, persistent or worsening symptoms warrant a call to your doctor. This includes continuing or increasing fever, persistent cough, or symptoms not improving after several days of taking the medication, as prescribed.
Specific Concerns
Consult your physician if you experience persistent nausea, vomiting, diarrhea (especially severe or bloody diarrhea), or significant changes in your bowel habits. Also, report any signs of neurological changes, such as confusion, seizures, or unusual changes in vision or hearing. Remember to mention any new medications you’ve started since beginning Bactrim.