Always inform your doctor about all medications you take, including over-the-counter drugs and supplements, before starting doxycycline. This helps prevent harmful drug interactions. Common side effects include nausea, diarrhea, and stomach upset. These usually are mild and resolve without treatment. However, severe diarrhea could indicate Clostridium difficile infection, requiring immediate medical attention.
Sun Sensitivity and Photosensitivity
Doxycycline increases your skin’s sensitivity to sunlight. Avoid prolonged sun exposure, use sunscreen with an SPF of 30 or higher, and wear protective clothing, especially during peak sun hours. If you experience a sunburn, contact your doctor. Photosensitivity reactions can manifest as rashes or blisters.
Other Potential Side Effects
Less common but potentially serious side effects include: inflammation of the esophagus (esophagitis), which may cause difficulty swallowing; liver problems, indicated by jaundice (yellowing of skin and eyes) or dark urine; and allergic reactions, such as hives, swelling, or difficulty breathing. Seek immediate medical help if you experience these symptoms. Doxycycline can also affect the gut flora, potentially leading to yeast infections (thrush). Women should be aware of the possibility of vaginal yeast infections.
Precautions and Contraindications
Do not take doxycycline if you are pregnant or breastfeeding. It can harm the developing fetus and enter breast milk. Do not use doxycycline if you have a known allergy to tetracycline antibiotics. People with kidney or liver problems should inform their doctor, as dosage adjustments may be necessary. Additionally, discuss doxycycline use with your doctor if you have a history of esophageal disorders.