Understanding the Basics: How Each Drug Works

These three medications–Cialis, Levitra, and Viagra–all belong to a class of drugs called phosphodiesterase-5 (PDE5) inhibitors. They work similarly but have subtle differences in their mechanisms and durations of action.

    Viagra (sildenafil): Viagra increases blood flow to the penis by inhibiting PDE5, an enzyme that breaks down cGMP. Increased cGMP levels relax the muscles in blood vessel walls, leading to improved blood flow. Its effects typically last 4-5 hours. Cialis (tadalafil): Cialis also inhibits PDE5, resulting in increased cGMP and improved blood flow. However, Cialis is a longer-acting drug, with its effects lasting up to 36 hours. This longer duration is due to its longer half-life. Levitra (vardenafil): Like Viagra and Cialis, Levitra works by inhibiting PDE5 and increasing cGMP levels, leading to improved blood flow. Its effects generally last 4-5 hours, similar to Viagra.

The key differences lie in their duration of action and how quickly they take effect. Viagra and Levitra generally work faster, while Cialis provides a longer-lasting effect. Your doctor will help determine which medication is best suited to your individual needs and health profile.

Remember that these medications require sexual stimulation to be effective. They don’t automatically cause an erection.

Onset of action: Viagra and Levitra often show effects within 30-60 minutes. Cialis may take longer, sometimes up to 2 hours, but its effects last significantly longer. Duration of action: Viagra and Levitra typically last 4-5 hours. Cialis’ effects can last up to 36 hours. Metabolism: Each drug is metabolized differently, influencing duration and potential side effects. Your doctor considers these factors when making recommendations.

It’s crucial to discuss any underlying health conditions or medications you’re taking with your physician before starting any of these drugs. They can assess your suitability and potential risks.