The Link Between Prednisone and Increased Stomach Acid Production

Prednisone, a corticosteroid, can stimulate your stomach to produce more acid. This happens because prednisone affects the production of hormones that regulate acid secretion. Higher acid levels increase your risk of heartburn and acid reflux.

Here’s what you need to know:

    Increased Gastric Acid: Prednisone directly influences your stomach’s parietal cells, leading to heightened acid production. Reduced Protective Mechanisms: Prednisone can also reduce the protective mucus lining in your stomach, making you more vulnerable to acid damage. Lower Esophageal Sphincter Tone: The muscle at the bottom of your esophagus, which normally prevents acid reflux, may relax more readily under the influence of prednisone, allowing stomach acid to flow back up.

If you experience heartburn or reflux while taking prednisone, consider these steps:

Dietary Adjustments: Avoid trigger foods like fatty meals, spicy dishes, chocolate, and caffeine. Lifestyle Changes: Eat smaller, more frequent meals. Avoid eating before bed. Elevate your head while sleeping. Over-the-Counter Medications: Antacids or H2 blockers (like ranitidine or famotidine) can help neutralize stomach acid. Consult Your Doctor: Discuss your symptoms with your physician. They may prescribe stronger medications like proton pump inhibitors (PPIs) or recommend alternative treatment strategies.

Remember, this information is for general knowledge and shouldn’t replace professional medical advice. Always consult your doctor before making changes to your medication or treatment plan.