Always inform your doctor about all medications you’re taking, including over-the-counter drugs, herbal supplements, and vitamins. This includes nitrates used for chest pain, as combining them with tadalafil can cause a dangerous drop in blood pressure.
Certain medications can affect how tadalafil works, or vice versa. Alpha-blockers, commonly used for high blood pressure or prostate problems, may increase the risk of low blood pressure when taken with tadalafil. Your doctor might adjust your dosages or recommend alternatives.
Be aware that tadalafil can interact with antifungal medications like ketoconazole or itraconazole, potentially raising tadalafil levels in your blood. Your doctor should monitor you carefully if you’re using these medications concurrently.
If you have a history of heart problems, liver disease, or kidney disease, discuss your tadalafil use with your physician. These conditions can influence how your body processes the medication.
| Nitrates | Severe drop in blood pressure | Avoid concurrent use. |
| Alpha-blockers | Increased risk of low blood pressure | Dosage adjustments may be needed. |
| Azole antifungals (ketoconazole, itraconazole) | Increased tadalafil levels | Careful monitoring by your doctor. |
| CYP3A4 inhibitors (e. g., ritonavir) | Increased tadalafil levels | Dosage adjustments may be needed. |
This information does not replace professional medical advice. Always consult your doctor before starting or stopping any medication.
