Taking 500mg of naproxen can cause various side effects. Common ones include stomach upset, heartburn, nausea, and diarrhea. These are usually mild and resolve without treatment. However, more serious reactions are possible.
Gastrointestinal Issues
Naproxen, like other NSAIDs, increases the risk of gastrointestinal bleeding, ulcers, and perforation. This risk rises with higher doses and prolonged use. If you experience black, tarry stools, bloody vomit, or severe stomach pain, stop taking naproxen and seek immediate medical attention. Consider taking it with food or a protective medication, such as a proton pump inhibitor, if prescribed by your doctor.
Cardiovascular Risks
Studies suggest that high doses of naproxen can increase the risk of heart attack and stroke, particularly with long-term use or in individuals with pre-existing cardiovascular disease. Regular monitoring of blood pressure and cholesterol is advised, especially for high-risk patients. Consult your doctor before initiating naproxen, especially if you have a history of heart or blood vessel problems.
Kidney and Liver Effects
Naproxen can impair kidney function, especially in individuals with pre-existing kidney disease, dehydration, or those taking other medications that affect the kidneys. Liver damage is rare but possible. Unusual fatigue, jaundice (yellowing of skin or eyes), or dark urine warrant immediate medical evaluation.
Allergic Reactions
Allergic reactions to naproxen range from mild skin rashes to severe, life-threatening anaphylaxis. Symptoms like hives, swelling of the face, lips, or tongue, difficulty breathing, or dizziness require immediate emergency medical treatment. If you’ve experienced an allergic reaction to aspirin or other NSAIDs, you’re at higher risk for a reaction to naproxen.
Interactions with Other Medications
Naproxen interacts with several medications, including blood thinners, lithium, and certain diuretics. Always inform your doctor and pharmacist about all medications, supplements, and herbal remedies you are taking to prevent dangerous interactions. They can help you manage potential risks.
This information is not a substitute for professional medical advice. Always consult your doctor before starting or stopping any medication.