Gastrointestinal distress is common. Expect nausea, diarrhea, or stomach upset, often resolving within a few weeks. Drink plenty of water and consider taking Metformin with food to mitigate these effects. If symptoms persist or worsen, contact your doctor.
Weight loss is a frequent side effect; however, excessive or rapid weight loss warrants medical attention. Monitor your weight regularly and report any concerns.
Low blood sugar (hypoglycemia) is rare with extended-release Metformin but possible, especially if combined with other diabetes medications or if you’re fasting or exercising strenuously. Carry glucose tablets or a sugary snack as a precaution.
Lactic acidosis is a serious but uncommon complication. Risk factors include kidney disease, liver disease, heart failure, and excessive alcohol consumption. Your doctor will monitor your kidney function regularly. Report any unusual muscle pain, weakness, or shortness of breath immediately.
Vitamin B12 deficiency can develop over time. Your doctor may suggest periodic B12 level checks and supplementation if needed.
| Nausea, diarrhea, stomach upset | Take with food, increase water intake, contact doctor if symptoms persist |
| Weight loss | Monitor weight, report excessive or rapid loss |
| Hypoglycemia | Carry glucose tablets or sugary snacks, adjust medication as needed |
| Lactic acidosis | Report muscle pain, weakness, shortness of breath immediately |
| Vitamin B12 deficiency | Regular blood tests, potential supplementation |
This information is not a substitute for professional medical advice. Always consult your doctor before starting or changing any medication.


