Managing Prednisone-Induced Hyperglycemia

Monitor blood glucose levels regularly, ideally daily, especially in patients with a history of diabetes or risk factors. Target blood glucose control should be individualized, considering the patient’s overall health status and the need to balance glycemic control with other treatment goals.

Dietary modifications are crucial. Emphasize a diet low in refined carbohydrates and high in fiber. Consult a registered dietitian for personalized meal planning.

Increase physical activity. Regular exercise improves insulin sensitivity and helps manage blood sugar. Recommend at least 150 minutes of moderate-intensity aerobic activity per week.

Consider metformin as first-line therapy for hyperglycemia unresponsive to lifestyle changes. This medication improves insulin sensitivity and decreases hepatic glucose production.

If metformin is insufficient, insulin therapy may be necessary. Closely monitor blood glucose levels and adjust insulin dosage accordingly. Consult with an endocrinologist for optimal insulin regimen.

Regularly assess the patient’s overall health status to ensure that treatment of hyperglycemia doesn’t negatively impact other conditions. Adjust prednisone dosage as clinically indicated. Lowering prednisone dosage, when medically appropriate, can significantly improve glycemic control.

Educate patients about the signs and symptoms of hyperglycemia (increased thirst, frequent urination, fatigue) and instruct them to seek medical attention if these symptoms worsen.