Is Aleve an Anti-Inflammatory? Understanding its Mechanism

Yes, Aleve (naproxen sodium) is a nonsteroidal anti-inflammatory drug (NSAID). It works by inhibiting the production of prostaglandins.

Prostaglandins: The Inflammation Players

Prostaglandins are hormone-like substances your body produces in response to injury or inflammation. They contribute to pain, swelling, and fever. By blocking cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2, Aleve reduces prostaglandin synthesis.

COX-1 and COX-2: A Closer Look

COX-1 plays a role in protecting your stomach lining and promoting blood clotting. COX-2 primarily contributes to inflammation and pain. While Aleve affects both COX-1 and COX-2, its impact on COX-2 is greater, leading to its anti-inflammatory effects. This dual action explains both the pain-relieving and anti-inflammatory properties, but also carries the risk of side effects like stomach upset. Always follow prescribed dosage and consult your doctor if you have concerns.