Always inform your doctor about all medications you are taking, including over-the-counter drugs, supplements, and herbal remedies, before starting Estrace cream. This includes antidepressants, especially SSRIs and SNRIs, which can interact and potentially alter Estrace’s effectiveness or increase the risk of side effects. Certain antibiotics, antifungals, and anticonvulsants may also affect Estrace’s metabolism.
Grapefruit juice can significantly impact the metabolism of many medications, including some that contain estrogen. Avoid grapefruit juice while using Estrace cream unless your doctor advises otherwise. This is because grapefruit inhibits enzymes in the liver that break down certain drugs, potentially leading to elevated blood levels and increased side effects.
Your doctor might adjust your Estrace cream dosage based on these interactions. Regular monitoring and open communication with your healthcare provider are vital for safe and effective treatment. If you experience unexpected side effects, contact your physician immediately. They can assess the situation and recommend the best course of action, potentially including dosage adjustments or alternative treatments.
Certain medications can increase the risk of blood clots, a potential side effect of estrogen therapy. Your doctor will carefully evaluate your risk factors and consider this possibility when determining your Estrace cream dosage and monitoring your progress.
