Grapefruit juice significantly increases amlodipine levels, potentially causing dangerously low blood pressure. Avoid grapefruit while taking this medication.
Amlodipine can interact negatively with certain other blood pressure medications, such as other calcium channel blockers. Your doctor should carefully review all your medications to avoid dangerous drug interactions.
Simultaneous use with certain antifungals (like ketoconazole) or HIV protease inhibitors can boost amlodipine concentrations, necessitating dose adjustments. Your physician will determine the appropriate course of action.
Patients with severe aortic stenosis or hypertrophic obstructive cardiomyopathy should exercise caution, as amlodipine can exacerbate these conditions.
Pregnancy and breastfeeding require careful consideration and consultation with your doctor. Amlodipine may pass into breast milk.
Individuals with liver impairment might require dose adjustments due to the altered metabolism of amlodipine. Your doctor will monitor your condition closely.
Always inform your doctor of all medications, including over-the-counter drugs and herbal remedies, before starting amlodipine.
