This combination medication treats type 2 diabetes by improving your body’s response to insulin and decreasing glucose production. Glipizide stimulates insulin release from your pancreas, while metformin reduces glucose production in the liver and improves insulin sensitivity. This dual action often results in better blood sugar control than either drug alone.
Doctors typically prescribe this combination when lifestyle changes like diet and exercise aren’t enough to manage blood sugar levels. Expect regular blood glucose monitoring to assess the medication’s effectiveness. Your doctor will adjust dosages based on these results, aiming for optimal blood sugar control while minimizing side effects.
Common side effects include nausea, vomiting, diarrhea, and stomach upset (mostly from metformin). Glipizide can cause low blood sugar (hypoglycemia), characterized by symptoms like shakiness, sweating, and confusion. Immediate treatment involves consuming a sugary drink or snack. Less frequent side effects include weight gain and allergic reactions. Report any unusual symptoms to your physician.
Before starting this medication, inform your doctor about your complete medical history, including any allergies, kidney or liver problems, and other medications you take. This is particularly important because metformin can affect kidney function. Regular kidney function tests are commonly recommended during treatment.
While generally safe and effective, this combination isn’t suitable for everyone. Pregnant or breastfeeding women, individuals with severe kidney or liver disease, or those with a history of certain heart conditions may need alternative treatment options. Your doctor will assess your individual circumstances to determine the most appropriate course of action.
This information provides a general overview. Consult your doctor for personalized advice, dosage recommendations, and monitoring schedules. They will tailor treatment to your specific needs and health status. Always follow your doctor’s instructions carefully.
