Prednisone can significantly affect your digestive system. Be aware of potential problems and take preventative measures.
One common side effect is peptic ulcers. Prednisone reduces the production of protective mucus in your stomach lining, making you more vulnerable. This increased risk is especially pronounced with higher doses and prolonged use. Consider taking a proton pump inhibitor (PPI) or histamine-2 (H2) blocker, as prescribed by your doctor, to protect your stomach lining.
- Proton Pump Inhibitors (PPIs): These medications reduce stomach acid production more effectively than H2 blockers. Histamine-2 (H2) Blockers: These medications also decrease stomach acid, though less powerfully than PPIs.
Another concern is gastroesophageal reflux disease (GERD). Prednisone can weaken the lower esophageal sphincter, allowing stomach acid to flow back into the esophagus, causing heartburn and discomfort. Elevate your head while sleeping and avoid large meals close to bedtime. Over-the-counter antacids might offer some relief for mild symptoms, but always discuss any medication changes with your doctor.
Prednisone can also lead to nausea, vomiting, and diarrhea. These symptoms are typically dose-related and tend to improve when the dosage is reduced or stopped. Staying hydrated is crucial to manage diarrhea. If symptoms persist or worsen, consult your doctor immediately.
Pancreatitis, a serious inflammation of the pancreas, is a rarer but possible complication. If you experience severe abdominal pain, especially after starting prednisone, seek medical attention promptly.
Report any digestive issues to your doctor immediately. Early intervention improves outcomes. Follow your doctor’s instructions regarding dosage and duration of prednisone treatment. Discuss potential preventative medications like PPIs or H2 blockers with your doctor. Maintain a healthy diet and lifestyle.
