Amlodipine’s role in migraine prophylaxis remains somewhat controversial, with studies showing varied results. Some research suggests a modest reduction in migraine frequency for certain patients, particularly those with comorbid conditions like hypertension. However, it’s not a first-line treatment and its efficacy is less robust compared to established migraine preventatives.
Typical Dosage and Administration
The typical starting dose is 5mg once daily. Physicians may increase this to 10mg daily based on individual response and tolerance. Amlodipine is generally well-tolerated, but potential side effects include dizziness, swelling in ankles and feet, and headache. Close monitoring for these effects is necessary.
Patient Selection and Considerations
Amlodipine might be considered for patients with both migraine and hypertension, as it addresses both conditions. However, individual response varies significantly. Patients should discuss the risks and benefits with their neurologist or physician before initiating treatment. Alternative medications are often preferred for migraine prophylaxis due to more consistent evidence of efficacy. Regular monitoring of blood pressure is crucial during treatment. A trial period, typically several months, is needed to assess its impact on migraine frequency. If no significant improvement is observed, alternative preventative strategies should be explored.
