Avoid alcohol while taking Amoxicillin/clavulanic acid. Alcohol can increase the risk of side effects like nausea and vomiting.
Certain medications can interact negatively. Specifically, avoid taking oral contraceptives concurrently, as Amoxicillin/clavulanic acid may reduce their effectiveness. Consider alternative birth control methods during treatment.
Methotrexate is another medication requiring caution. Simultaneous use with Amoxicillin/clavulanic acid may increase the risk of methotrexate toxicity. Your doctor should carefully monitor your condition if you are taking both.
Medications Requiring Caution
Consult your physician before combining Amoxicillin/clavulanic acid with any of the following: anticoagulants (like warfarin), probenecid, or other antibiotics.
Herbal Remedies and Supplements
Some herbal remedies and supplements can interact with Amoxicillin/clavulanic acid. Always inform your doctor or pharmacist about all medications, vitamins, and supplements you’re taking. This includes herbal remedies like St. John’s Wort. Failure to do so might lead to unforeseen issues.
| Oral Contraceptives | Many brands | Reduced effectiveness |
| Anticoagulants | Warfarin | Increased bleeding risk |
| Methotrexate | Methotrexate | Increased toxicity |
