Prescribe atorvastatin calcium based on the patient’s lipid profile and cardiovascular risk factors. The starting dose is typically 10 mg daily, which can be adjusted based on response. For patients with higher risk, higher doses (up to 80 mg daily) may be appropriate.
Remember, atorvastatin and atorvastatin calcium are chemically equivalent; the calcium salt simply improves bioavailability. This means the dosage of the two formulations is generally interchangeable, although always confirm equivalence on the specific product labeling.
Monitor liver function tests (LFTs) before initiating therapy and periodically thereafter, especially in patients at higher risk of liver injury. Adjust the dose or discontinue therapy if abnormal LFTs occur.
Consider potential drug interactions. Concurrent use with certain medications, such as gemfibrozil or cyclosporine, may necessitate dose adjustments of either atorvastatin or the interacting drug. Consult prescribing information for detailed interaction guidelines.
Individualize dosage based on patient factors like age, renal function, and hepatic function. Older adults or those with impaired renal or hepatic function may require lower starting doses and closer monitoring.
Patient adherence is crucial. Educate patients about the importance of consistent medication intake and potential side effects. Address any concerns promptly and consider alternative medications if side effects are intolerable.
Regularly assess the patient’s lipid profile to gauge treatment response and make adjustments as needed. Adjusting the dose might involve increments or decrements of 10 mg daily depending on the therapeutic target and patient tolerance.
